Disabling the automated save function will prevent an error from appearing when the game's data storage if full.
Erasing the game' storage also deletes your game file.
There is an error that will break your game, happens when you try to transplant your fertilized egg into an npc that is already pregnant or is unable to get pregnant. Load an earlier save data.
Another error happens when you sire too many npcs at the same time, example: 5-10 pregnant modified broodmothers cowgirls, spawning hundreds of children at the same time. You will get a never ending loading screen at the end of the week. Eliminating those npcs or loading to an earlier save data will fix this one.
A bit late to post here, but hopefully these will help some folks avoid a headache or two.